Innovation projects

AUTOPLAN – Surgical Navigation System

Scope: surgery.

AUTOPLAN is an operation planning and control system.

It is a multifunctional complex that allows planning surgical operations based on preoperative MRI and CT studies by building a 3D model of internal organs and tissues.


The AUTOPLAN surgical navigation system (RU RZN 2019/8153 of 28.05.2019) belongs to high-tech medical care equipment.

It is based on the principle of infrared tracking, which has no negative impact on the medical staff or the patient.

Innovative navigation and intraoperative imaging technology helps surgeons effectively plan and perform operations with extreme accuracy. The intuitive interface helps accelerate the processes in the operating room.

The system allows the surgeon to continuously monitor surgical instruments in relation to the patient’s anatomical structures, avoiding damage to functionally significant areas and to display them in real time on the monitor screen.


ReviVR – a simulator for rehabilitation after a stroke

Scope: rehabilitation.

The ReviVR early verticalization simulator is a hardware and software complex for restoring motor activity. The system is based on virtual reality and biofeedback technologies. ReviVR combines visual, auditory and tactile impact on the perception of the patient with impaired motor function, simulating the process of walking.



ReviVR is a virtual reality simulator for passive rehabilitation of persons with impaired motor function of the lower extremities, with violations of spatial orientation and with visual impairments. The simulator uses the technology of combining virtual reality and biofeedback with the ability to solve cognitive problems.

ReviMOTION – a simulator for rehabilitation after a stroke

Scope: rehabilitation.

The ReviMotion game simulator is a hardware and software complex designed for the rehabilitation of children with various types of motor activity disorders, including children with cerebral palsy.


ReviMotion is a simulator for active motor rehabilitation and habilitation of persons for the restoration of the musculoskeletal system. The simulator uses an optical system for tracking the movements of the person being rehabilitated and biofeedback with auditory and visual effects and the ability to solve cognitive problems. The rehabilitation process takes place during the implementation of exercise therapy exercises in a playful way.


ReviBCI – a simulator for rehabilitation after a stroke

Scope: rehabilitation.

The ReviBCI allows you to register and analyze the electrical bioactivity of the brain to determine and confirm diagnoses.



The device allows you to register and analyze the electrical bioactivity of the brain to determine and confirm diagnoses.

Artificial gravity stand “Salyut” and a new method of physiotherapy with increased gravity

The leader  is Academician of the Russian Academy of Sciences, Professor G.P. Kotelnikov.

A fundamentally new physiotherapy apparatus has been developed, the active therapeutic factor of which is increased gravity, as well as methods for treating surgical and therapeutic patients.

The novelty of the proposed project lies in the fact that for the first time, as a therapeutic factor in patients with complicated fractures and vascular surgical diseases of the lower extremities, it is proposed to use moderate amounts of increased gravity created using an experimental short-range centrifuge. The validity of the therapeutic use of this physical factor – increased gravity – is confirmed by our experimental and clinical studies. The recognition of the pioneering development of gravitational therapy as a new medical technology was the receipt in 2006 by Academician of the Russian Academy of Sciences G.P. Kotelnikov and Professor A.V. new direction in medicine.

The consumers of these products can be medical institutions, rehabilitation centers, sanatorium-resort institutions that provide medical care to patients with the consequences of fractures (delayed bone fusion, false joint, chronic osteomyelitis, trophic ulcers), atherosclerosis of the vessels of the lower extremities, arterial hypertension.

Basic principles and purpose of the technology: Therapeutic effect is achieved by rotation on the developed short-range electric centrifuge and simultaneous dosed muscle load on the lower limbs. Under the influence of centrifugal force, an additional blood flow to the lower extremities occurs. Due to the effect of hypergravity, there is an active development of collateral circulation, elimination of tissue ischemia, improvement of tissue metabolism, stimulation of periosteal and endosteal bone formation. The technology has proven itself in traumatology and orthopedics, surgery and other areas of medicine. Technologies are patented in the Russian Federation.

Innovative combined antimicrobial agents for local treatment of wounds and wound infections of various origins

Supervisor  – Doctor of Medical Sciences, Associate Professor A. V. Kolsanov.

Basic principles and purpose of technology:Combined antimicrobial agents in the form of a solution, ointments and wound dressings have been developed and patented in the Russian Federation, which are highly effective in the local treatment of patients with wounds and wound infection of the skin and soft tissues of various etiologies. The innovative novelty of the project lies in the fact that when developing combined antimicrobial agents, their high efficiency was achieved due to the rational selection of several chemically and physically compatible pharmacopoeial preparations that, when combined, can mutually enhance activity and expand the spectrum of antimicrobial action. As a result of the studies, the composition and concentrations of incoming pharmacopoeial preparations in the combined antimicrobial agents developed by us were selected. It is important to have different dosage forms: solution, ointments on a different basis,

Development and production of medical devices – laser biophotometer “Linsor” and “Combis”

Head  – Professor B. N. Zhukov

Basic principles and purpose of the technology: The principle of operation of the medical device “Linsor” is based on the reflection of laser radiation from the surface of the skin and capillaries. The use of the device allows diagnosing microcirculation disorders, selecting the right drug therapy, and performing graphic registration of the results. The principle of operation of the Combis medical device is based on fine spraying of medicines with simultaneous laser infrared radiation. “Combis” is used to treat trophic and purulent lesions of the skin.

There are patents of the Russian Federation for the developed medical devices and technologies for their application.

Device for guided infusion therapy

Due to the lack of a device in world practice that would control the rate and volume of administered drugs according to the parameters of a particular patient, a device is proposed for automatic control of the volume of infusion therapy, which will allow real-time control of the volume of fluid replaced in a particular patient, and by controlling the operation of the perfusor , change the qualitative and quantitative ratio of infusion-transfusion therapy when the patient’s systemic hemodynamics changes, and therefore minimize complications in patients and promptly notify medical personnel about changes in the patient’s condition.

Intravascular measurement of parameters by displaying a pressure curve on a graphic display and data on a monitor board is the most convenient and reliable way to continuously monitor the parameters of the vascular system.

Digital signal processing of the intravascular pressure sensor in the monitor allows you to determine the necessary parameters of blood pressure. The pressure transducer used for intravascular measurements in monitoring systems contains a sensing element that is affected by blood pressure. The sensor includes a catheter fixed in the vessel under study. The sensing element, which converts the pressure value into an electrical signal, is structurally placed outside the catheter. In modern designs of pressure sensors, the sensitive element is located at the tip of the subclavian catheter and is separated from the blood by a thin membrane.

The consumer is the department of resuscitation, anesthesiology and intensive care, oncology, cardiology. The device is environmentally friendly. The estimated final price of the proposed device is 35 thousand rubles. (no analogues).

Development of new bone-replacing materials

Scope: traumatology, dentistry, maxillofacial surgery.

A new implantation material has been created (a composite material based on titanium carbide with a nickel-titanium bond obtained using the technology of self-propagating high-temperature synthesis (SHS) from titanium, carbon and nickel powders) based on biocarbon ceramics with through porosity.

This material solves the following problems: distribution and availability of implant treatment among the population, dissemination of tissue engineering technologies and transplantation of combined implants with stem cells, shortening of treatment periods due to accelerated osseointegration processes (bone tissue ingrowth), reduction in the number of complications in the postoperative period, increase in biocompatibility, reduction of allergization and sensitization of the population.

Development, creation and organization of serial production of a complex of metal fixators

Scope: traumatology, orthopedics and maxillofacial surgery.

An intramedullary nail for lockable osteosynthesis has been developed. The rod is a tube of triangular section with a guide and nipple parts, on the outer surfaces of the tube there are fixing ribs. Before assembly, the rod is compressed, during the operation, a saline solution is supplied into the internal cavity of the rod under pressure, expansion occurs, as a result of which the rod takes the form of a bone marrow canal in cross sections throughout its working length and securely fixes bone fragments. The advantage of the proposed design is the ability to minimize damage to the bone marrow during the transition of the rod to the expanded state and reverse narrowing, as well as the ability to reduce damage to the bone marrow canal by reducing the maximum pressure on its surface.

Development and creation of a device for setting tuberculin samples (analogue of a scarifier)

Scope: tuberculin diagnostics.

A device for conducting skin tests with tuberculin has been developed. The device contains a handle made in the form of a plate with a thread 25 mm long and 5 mm wide and a working part made in the form of a needle 1 mm long and 0.2 mm in diameter, coming out of the central part of the handle base, which serves as a limiter when piercing the skin. This design creates a skin puncture with minimal damage to the dermal layer.

Creation and approbation of technology for the production of a species-specific probiotic for animal husbandry

Scope: animal husbandry.

A technology has been developed for obtaining a uterine medium in which a sufficient amount of effective microorganisms of the lactic acid flora of the broiler poultry intestine has been obtained. The obtained uterine medium is further used to obtain a specific probiotic in industrial production. Approbation was carried out on the use of a species-specific probiotic in industrial conditions for fattening broiler poultry per 10,000 heads.

Development and creation of new drugs based on plant materials

Scope: dentistry and maxillofacial surgery.

A phytocomposition based on several types of medicinal plant raw materials (MPR) has been developed, which have antimicrobial, anti-inflammatory, hemostatic, regenerating, local immunocorrective and anesthetic pharmacological activity for the treatment and prevention of dental diseases. The phytosubstance is a complex tincture (total water-alcohol extract from 5 types of medicinal plant materials) intended for inclusion in therapeutic and prophylactic toothpastes, as well as for creating medicines based on it: gel, spray, etc.

Development of new antibacterial wound coverings

Scope: surgery, combustiology, dermatology.

A wound dressing with a phytotherapeutic substrate has been developed for the treatment of surgical infections of the skin. The wound dressing is a textile base made of knitted fabric, on which a composition of a biocompatible phytotherapeutic substrate is applied. Wound dressing has a long-term antimicrobial, analgesic, soothing effect. The treatment layer contains a combined phytotherapeutic substrate consisting of echinacea, eucalyptus and calendula. A method has been developed for the treatment of wounds and wound infection of the skin and soft tissues, which ensures the restoration of the integrity of the anatomical and functional structures of the affected skin by exposure to phytotherapeutic agents in a certain concentration in the wound covering.

Creation of a device for determining central venous pressure

Scope: therapy.

A device has been developed for automatic monitoring of the level of the patient’s central venous pressure, which allows real-time control of the volume of replaced fluid by controlling the operation of the infusion pump, changing the qualitative and quantitative ratio of infusion-transfusion therapy, thereby minimizing the number of complications in patients.

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